What is Regenerative Medicine?


Regenerative medicine makes use of cells, biomaterials, and molecules to fix structures in the body that do not function properly due to disease or injury.

What sets regenerative medicine apart from many traditional drugs is that the latter mostly treat symptoms, whereas the former aims to treat the root cause of a patient’s condition by replacing lost cells or organs, or by fixing a faulty gene.

Orthopedic Regenerative Medicine is a Game Changer

Regenerative medicine holds great promise for orthopedic surgery. For both chronic and acute pain patients the widening scope of minimally invasive orthopedic treatments available is exciting. While surgeries, such an total knee replacement, produce excellent outcomes and may be the best choice for some patients, the world of regenerative medicine is a game changer for athletes and those seeking daily living pain relief alike.  Techniques and technology advancements such as stem cell therapy, platelet rich plasma therapy, gene transfer and tissue engineering, are expected to move the field of orthopedics into a new era. The research regenerative medicine bench is solidly in play at the orthopedic clinical bedside.


What is PRP Therapy?

Platelet-Rich Plasma (PRP) Therapy is a conservative and holistic approach to increase the healing speed of damaged tissues. PRP uses super concentrated platelets and it is a natural choice of treatment for musculoskeletal pain such as osteoarthritis, plantar fasciitis, neuropathy, degenerative disorders, and other sports injuries. It is commonly done, complementing orthopedic surgeries to intensify the healing process.

How is PRP Therapy Administered?


A qualified professional will draw a small amount of blood and spin it in a centrifuge, isolating the platelets for your treatment. The site of injury is treated using the PRP preparation. PRP is carefully injected into the injured area combined with local anesthesia. The treatment area will be cleansed before applying a local anesthetic to guarantee a more pleasant experience. Then the patients own PRP will be injected into the predetermined treatment area. This will trigger the body’s natural healing process. It is expected for patients to experience pain for the first two weeks after the procedure, however pain is reported from mild to minimal.

Benefits of PRP Therapy


PRP therapy may be used to improve healing after surgery for some injuries. The ultimate goal of PRP is to eliminate pain through healing while providing results that last. Research studies have shown that PRP therapy can be effective in relieving pain and helping patients return to their normal lives.

Who Needs PRP Therapy?


Here at Regenerative Complete, we use regenerative medicine as an advanced treatment method for:

  • Erectile Dysfunction

  • Nutrients

  • Rehydration

  • Recovery & Performance

  • Tendon & Muscle Repair

  • Muscle Tone

  • Weight Management

  • Aesthetic Dermatology

  • Surgical Recovery

  • Soft Tissue Injuries

  • Plantar Fasciitis

  • Inflammation


What is Involved in Regenerative Therapy?


If Dr. Robins determines you are a good candidate for Regenerative therapy, it is important to understand exactly what to expect from the procedure, including all possible outcomes. Regenerative therapy involves one of two options. Using cells from a donor or autograft harvesting. If allograft cells are chosen we simply pull the prescribed volume of cells into a syringe and Dr. Robins will inject into the affected joint. Autograft harvesting requires a two step process. First, Dr. Robins uses your own blood or bone marrow to extract the needed stem cells. He must isolate the stem cells and the platelet-rich plasma (PRP) using a centrifuge. The stem cells and PRP are then injected into the targeted treatment area of your affected joint.


The procedure is performed on an outpatient basis and you can go home afterward to rest.


How Fast are the Results Regenerative injections?



Immediately following the injection,  the regenerative therapy chosen goes to work restoring the diseased areas. Due to the nature of these injections, it takes time to see noticeable results. You may start to experience some relief of your pain within three weeks of the injection, as inflammation starts to decrease.


As more time passes and the injections continue to do their job, you will notice a more significant difference in your symptoms.


For many people, it only takes one injection procedure to experience long-term pain relief. In some cases, results last a lifetime. But for others, If you suffer from more serious conditions involving degeneration of the discs or joints, you may need additional injections, based on Dr. Robin’s recommendation.


Not everyone is a candidate for Regenerative Therapy. However, if chronic pain is limiting your ability to perform your job or participate in activities you enjoy, a Regenerative Therapy consultation may be worthwhile to restore your quality of life.


Orthopedic Areas of Interest for Regenerative Therapies.



  • Articular Cartilage – Damage to the articular cartilage following an injury has poor potential for repair and can lead to arthritic changes many years after injury. Recent studies have shown favorable outcomes and better knee scores at 2 year follow up for regenerative Therapies compared to current techniques of microfracture and autologous chondrocyte implantation.

  • Bone – Trauma and some pathological conditions can lead to extensive bone loss, which requires transplantation of bone and other bone substitutes to restore structural integrity. A large number of studies have shown great potential for Regenerative Therapies to repair critically sized bone defects, noting better bone growth and more robust bone formation than controlled groups.

  • Tendons and Ligaments – Injuries to tendons and ligaments heal by forming inferior quality tissue. Autografts, allografts, and resorbable materials have been used to repair defects in tendons and ligaments, but these carry risks including donor site morbidity, scar formation, and tissue rejection. A number of studies on the use of Regenerative Therapies to improve the repair of tendons and tendon defects have been carried out with favorable results when measured in histology and tissue strength. The use of Regenerative Medicine with tissue allografts enhances the graft and improves the biomechanical properties compared to control studies.

  • Meniscus – Most tears of the meniscus occur in avascular zones with little or no potential for repair. Standard biological healing processes produce limited results and meniscectomy (removal of all or part of the torn meniscus) has been shown to have a strong association with subsequent development of osteoarthritis. Recently, studies have shown that self-paced therapy including Regenerative Joint injections demonstrates biological healing and adherence of meniscal tears in avascular zones.

  • Spine – Degeneration of intervertebral discs is a common cause of back pain and morbidity. Most patients are treated conservatively with improvement in approximately 90%. If conservative treatment proves ineffective, the surgical options for discogenic back pain are limited and usually invasive. Cell-based tissue treatments, including Regenerative Joint  injections for degenerative disc subjects have been shown to diminish the incidence of low back pain, with clinical results noting improvement in back pain and MRI results showing regeneration of disc tissue. 

  • Osteonecrosis – Osteonecrosis or avascular ischemia of the hip can be associated with progression to an advanced arthritic joint. Standard treatment for osteonecrosis has included core decompression with limited results. Studies report improvement in hip scores in patients treated with Regenerative treatments and core decompression versus core decompression alone

Are Orthopedic Regenerative Therapies Covered by My Insurance?



Most clinics will tell you no.  They will often say because stem cell injections are considered investigational for orthopedic applications, most insurance companies will not cover the cost. At Regenerative Complete, we have a process that allows patients to often utilize their insurance plans. Please contact our office to discuss payment options.


What is the Cost of Orthopedic Regenerative Therapies?



Your out-of-pocket cost will vary, depending upon whether you have a Regenerative Therapy independent of or in conjunction with another surgical procedure.


What is Peptide Therapy?


A peptide is a short chain of amino acids that are linked together, and can be thought of as a small protein. To date, over 7,000 naturally-occurring peptides have been identified. In our bodies, these small proteins typically act as signaling molecules. They bind to receptors on the cell surface and tell other cells and molecules what to do.


Peptide therapy, or the use of specific peptides in treatment, has gained great popularity in recent years. This is due largely to the fact that these peptides are highly specific (i.e., only do what you want them to do) while also being well-tolerated and safe. As of January 2015, there were over 60 US FDA-approved peptide medications, 140 peptide drugs being evaluated in clinical trials, and 500 in pre-clinical development.


Most of these peptide drugs are administered intradermally, but can also come in the form of transdermal creams, nasal sprays, and oral tablets.

What Conditions Does Peptide Therapy Address?


Because these peptides are so numerous and variable in structure, their effects are likewise varied and wide-ranging. One class of these peptides are known as growth hormone secretagogues, and cause the secretion of one’s own, natural hGH in the body. These peptides have been shown to be very useful in the treatment of age-related conditions, osteoporosis, obesity, various chronic inflammatory diseases, building muscle mass and erectile dysfunction and have several advantages over traditional hGH administration.


Another type of peptide drug is composed of part of the hGH molecule that is responsible for fat cell death, and has been shown to be very effective as an anti-obesity drug. In addition to decreasing inflammation, these drugs lead to increased lean muscle mass and decreased body fat.


A certain class of peptide drug has been used to help prevent skin cancer by increasing the melanin in one’s skin, causing a darkening effect that mimics a quality sun tan. This peptide has also been shown to increase lean muscle mass and improve sex drive.

Would You Benefit From Peptide Therapy?


Peptide therapy encompasses numerous different drugs with varied effects, ranging from immune modulation and tissue repair to fat loss and ED to muscle building. Many patients have seen very positive results with CFS, Hashimoto’s thyroiditis, Lyme disease, and fibromyalgia, orthopedics among other conditions. Ask your provider at Regenerative Complete or call us at 865-888-4721 to find out if peptide therapy is right for you.


What Peptide Therapy is Available?


Thymosin Alpha-1

Thymosin alpha-1 (T α 1) is a peptide, or small protein, consisting of 28 amino acids. T α 1 is produced naturally by the thymus gland. The thymus is located behind the sternum and between the lungs, and is where immune cells known as T cells mature and are released, prompted to do so by the T α 1 peptide. T cell production and action within the body is vital to adaptive immunity—the mode by which immune cells are able to recognize and eradicate foreign invaders.


T α 1 has been found to have a profound effect on the immune system, and is the active ingredient in the immune modulating drug, Zadaxin®. Zadaxin® is used to treat hepatitis B and C, and has been studied extensively for its ability to support an immune system that has been suppressed by chemotherapy in cancer patients.


Specifically, T α 1 has been shown to enhance the function of certain immune cells called T and dendritic cells. This is very important to anyone with a depressed immune system or suffering from an infection, as these white blood cells play pivotal roles in the body’s defense process. T cells, for example, come in two forms: killer and helper T cells. Killer T cells are responsible for hunting down and destroying our body’s own cells that are cancerous or infected with bacteria or viruses. Helper cells work with the other cells of the immune system to orchestrate and carry out appropriate immune responses.


Dendritic cells are just as valuable to our body’s defense system. These cells gather important information about infection or the presence of cancerous cells, and communicate with the T cells, who then act appropriately to eradicate the unhealthy cells and stop the infection or cancer growth.


T α 1 itself has been shown to exhibit antibacterial and antifungal properties, suppress tumor growth, increase vaccine effectiveness, and protect against oxidative damage.


Studies have shown that individuals fighting infection have a lower amount of circulating T α 1 and suppressed helper T cell numbers compared to healthy individuals. This is problematic, as optimal immune function is vital to recovery from infection. Supplementation with T α 1 has the potential for great therapeutic benefit for patients suffering from infection or autoimmune disease.


In addition to its use in the treatment of Hepatitis, AIDS, and cancer, T α 1 has shown great promise in the treatment of Lyme disease. This is unsurprising when one considers the large role the immune system plays in combating the disease.


T α 1 assists the immune system in the location and eradication of the Lyme bacteria and infected cells, while helping to prevent oxidative damage, thereby decreasing inflammation and enabling better quality of life throughout treatment.


The T α 1 peptide can be administered via subcutaneous injection. T α 1 has been found to be very safe, and there have not been any documented side effects associated with its administration. It is approved in more than 37 countries for the treatment of hepatitis B, hepatitis C, and as an adjunct to chemotherapy and various vaccines.


Thymosin Beta 4

Thymosin beta 4 (Tβ4) is the predominant form of thymosin in our bodies. It has been found in high concentrations in wound tissue and certain blood cells involved in clotting, signifying its important role in the healing process. In fact, recent studies have revealed that the first gene to be upregulated after an injury is the Tβ4 gene. As the body begins the recovery process, Tβ4 aids in the creation of new vessels in the injured area, which carry blood, nutrients, and reparative substances to the site. Tβ4 also has anti-inflammatory properties, and works to decrease the amount of inflammatory substances, called cytokines.


Inflammation plays a large role in many of the symptoms associated with a large number of conditions (i.e., Lyme disease, CFS, FM, autoimmune diseases, infections, etc.), making the potential impact of Tβ4 quite extensive.


The discovery of the role of Tβ4 in the process of immune regulation has lead to its use as a valuable therapeutic agent. Tβ4 has been used in the treatment of HIV, AIDS, Influenza, colds, and various infections. It has been utilized in the management of various inflammatory conditions, as well as part of treatment following heart attack due to its cardio and neuroprotective effects.


Tβ4 has been used at our clinic with a great deal of success in patients suffering from Lyme disease or other infectious and/or inflammatory conditions. Tβ4 is very well tolerated and has not been found to cause any significant side effects. It can be taken on its own or in conjunction with an existing therapy, making it a versatile and valuable drug.


Growth Hormone Secretagogues (GHSs)


This class of peptides includes several therapeutics that stimulate growth hormone (hGH) secretion. Each peptide varies slightly as far as structure and mechanism of action. Thus, a certain peptide may be preferred depending on the patient’s health status and desired outcome. GHSs include: CJC 1295, GHRP 2, GHRP 6, Hexarelin, and Ipamorelin.


CJC 1295

This particular peptide offers therapeutic benefits similar to those of hGH. CJC 1295 is a growth hormone releasing hormone (GHRH) analogue. In other words, it is a molecule that serves the same purpose as does GHRH—the hormone that stimulates the anterior pituitary to release hGH. However, unlike GHRH, which has a half-life of only minutes after IV administration, CJC 1295 is able to remain active in the body for extended periods due to its ability to bind to a protein in the blood known as albumin and avoid degradation by various enzymes. CJC 1295 increases an important growth factor, IGF-1, in addition to hGH, leading to fat loss, lean muscle growth, and enhanced sleep.


AOD 9064

This peptide is a modified fragment of hGH which contains the portion of the molecule that is believed to be responsible for hGH’s anti-obesity effects. The peptide has been shown to increase fat burning without the increase in blood sugar and growth rate that has been seen with hGH itself. AOD 9604 has been deemed safe for chronic use by the FDA, receiving Human GRAS status in 2014. In addition to its utility as an anti-obesity peptide, AOD 9604 has been shown to have very favorable cartilage repair and regenerative properties, especially when paired with peptide BPC 157.


Bremelanotide PT 141

Bremelanotide PT 141 was developed from Melanotan II, targeting its aphrodisiac effects. This peptide has been shown to have a substantial effect on libido, generating sexual arousal in both men and women within minutes of administration. It has been shown to be effective in treating erectile dysfunction, even in men who have not responded to other ED treatments, such as Viagara. This peptide is also able to cross the blood-brain-barrier, bypassing the vascular system and acting at the level of the central nervous system. This property gives Bremelanotide an advantage over traditional ED drugs, which can decrease blood pressure to dangerous levels. This peptide can be administered as a nasal spray, making its use convenient and discreet.



Cerebrolysin—also known as FPE 1070—is a synthetic nootropic drug. Nootropic drugs are substances that enhance cognitive functions such as memory, creativity, and motivation in otherwise healthy individuals. This peptide is extremely small, allowing it to penetrate the blood-brain barrier and act directly on the neurons of the central nervous system. Cerebrolysin has been found to improve the metabolic activity of brain tissue, shield neurons from harmful substances, and stimulate the peripheral and central nervous systems. In addition to its utility as a nootropic substance, the drug has potential as part of a treatment plan addressing Alzheimer’s disease, stroke, and moderate to severe head injury.

Book Your Consultation Today!

Talk To A New Patient Coordinator Today!